Search results for "Bovine genome"

showing 3 items of 3 documents

Genome-wide detection of copy-number variations in local cattle breeds

2019

The aim of the present study was to identify copy-number variations (CNVs) in Cinisara (CIN) and Modicana (MOD) cattle breeds on the basis of signal intensity (logR ratio) and B allele frequency of each marker, using Illumina’s BovineSNP50K Genotyping BeadChip. The CNVs were detected with the PennCNV and SVS 8.7.0 software and were aggregated into CNV regions (CNVRs). PennCNV identified 487 CNVs in CIN that aggregated into 86 CNVRs, and 424 CNVs in MOD that aggregated into 81 CNVRs. SVS identified a total of 207 CNVs in CIN that aggregated into 39 CNVRs, and 181 CNVs in MOD that aggregated into 41 CNVRs. The CNVRs identified with the two softwares contained 29 common CNVRs in CIN and 17 co…

cinisara0303 health sciencesFuture studies0402 animal and dairy scienceBovineSNP50K BeadChip Cinisara genomic variation Modicana04 agricultural and veterinary sciencesComputational biologyBiology040201 dairy & animal scienceGenome03 medical and health sciencesBovine genomeSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoAnimal Science and ZoologyCopy-number variationgenomic variationKEGGBovineSNP50K beadchipAllele frequencyGeneGenotypingmodicana030304 developmental biologyFood Science
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An initial comparative map of copy number variations in the goat (Capra hircus) genome

2010

Abstract Background The goat (Capra hircus) represents one of the most important farm animal species. It is reared in all continents with an estimated world population of about 800 million of animals. Despite its importance, studies on the goat genome are still in their infancy compared to those in other farm animal species. Comparative mapping between cattle and goat showed only a few rearrangements in agreement with the similarity of chromosome banding. We carried out a cross species cattle-goat array comparative genome hybridization (aCGH) experiment in order to identify copy number variations (CNVs) in the goat genome analysing animals of different breeds (Saanen, Camosciata delle Alpi,…

BreedingGenomePolymerase Chain ReactionSettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoMOUSE STRAINSChromosome regionsCapra hircusGOATCopy-number variationANGORA-GOATSGENE-EXPRESSIONGenetics0303 health sciencesComparative Genomic HybridizationGenomeGoatsChromosome Mapping04 agricultural and veterinary sciencesBovine genomeDatabases Nucleic AcidBiotechnologyResearch Articlelcsh:QH426-470DNA Copy Number VariationsSEGMENTAL DUPLICATIONSlcsh:BiotechnologyMolecular Sequence DataBiologyFluorescenceStructural variationPRODUCTION TRAITSBirds03 medical and health sciencesFAMILY BOVIDAEGene mappinglcsh:TP248.13-248.65Sequence Homology Nucleic AcidGeneticsFINE-SCALEAnimalsHumansFalse Positive Reactions030304 developmental biologyCOPY NUMBER VARIATION0402 animal and dairy scienceReproducibility of Results040201 dairy & animal scienceChromosomes MammalianDNA-SEQUENCESSTRUCTURAL VARIATIONlcsh:GeneticsCANDIDATE LOCIcopy number variation goatsCattleComparative genomic hybridizationBMC Genomics
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A first comparative map of copy number variations in the sheep genome.

2011

article i nfo We carried out a cross species cattle-sheep array comparative genome hybridization experiment to identify copy number variations (CNVs) in the sheep genome analysing ewes of Italian dairy or dual-purpose breeds (Bagnolese, Comisana, Laticauda, Massese, Sarda, and Valle del Belice) using a tiling oligonucleotide array with ~385,000 probes designed on the bovine genome. We identified 135 CNV regions (CNVRs; 24 reported in more than one animal) covering ~10.5 Mb of the virtual sheep genome referred to the bovine genome (0.398%) with a mean and a median equal to 77.6 and 55.9 kb, respectively. A comparative analysis between the identified sheep CNVRs and those reported in cattle a…

Ovis ariesDNA Copy Number VariationsRuminantSheep breedsaCGH; Comparative map; Copy number variation; Ovis aries; Ruminants; Sheep breedsGenomicsOvis arieBiologyGenomeChromosomesSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciencesaCGHChromosome regionsGeneticsAnimalsCopy-number variationGene030304 developmental biologyOligonucleotide Array Sequence AnalysisGeneticsCOMPARATIVE MAPPING0303 health sciencesComparative Genomic HybridizationGenomeSheepCopy number variation0402 animal and dairy scienceComparative Genome HybridizationChromosome Mapping04 agricultural and veterinary sciencesRuminantsbiology.organism_classification040201 dairy & animal scienceBovine genomeSardaCattleComparative mapGenomics
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